![]() The app can recover over 400 different file formats, and the data recovery process is so straightforward that even less experienced users can figure it out on their own. That said, Disk Drill is a trusted Mac cleaner, so you can leave everything up to it and save yourself valuable time.Īs we’ve already mentioned, Disk Drill excels at recovering lost files after an accidental deletion, hardware failure, or some other data loss incident. If you’re worried that an important file could find its away among junk files, then you can filter the scan results by file type, keywords, file size, and several other criteria and manually verify that the files you’re deleting are really unnecessary. “Great product and awesome customer service!” That’s because it comes with a truly unlimited free cleanup module that makes it possible to easily identify and visualize all files that are taking up a lot of space and get rid of them in an instant. Users can try all features for free and unlock unlimited junk removal for $39.95 per year.ĭisk Drill is actually a data recovery software first and a Mac file cleaner second, but that doesn’t stop it from ranking high on our list of the top 10 best free Mac cleaners. In addition to performing deep system cleaning, CleanMyMac X can neutralize malware threats, tweak various system settings, uninstall or reset apps, and securely delete sensitive files. Because the cleaner has been in development for over 10 years, you can be sure that the database contains all junk commonly found on modern Macs, including large and old files, Trash Bins, iTunes junk, mail attachments, and so on. “CleanMyMac X offers a variety of easy-to-use tools that can quickly free up space on your device and get rid of suspicious files.”ĬleanMyMac X is able to tell useful files from those that can be safely deleted thanks to the constantly updated Safety Database. This feature-packed app boasts a polished user interface and a whole host of useful cleaning features, making it possible to get rid of junk in all corners of your macOS with a single click. ![]() When it comes to Mac cleaners, you would be hard-pressed to find a more popular solution than CleanMyMac X by MacPaw.
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![]() Moreover, it boosts your productivity to work with everything you need to read, annotate and manage PDF files on the go. With a clean and easy-to-use interface, It may be your last and best PDF Reader & Editor. Overview of PDF Reader Pro APK for Android It is the best PDF Reader to enhance your productivity. ・ Ever feel tired of reading large files? Try Text-to-Speech(TTS).Free Download PDF Reader Pro - Reader & Editor MOD Version Unlocked Ad-Free APK for Android Phones and Tablets. Password protects sensitive documents and authorization to edit, copy, modify or print PDFs.・ Convert scanned PDFs into editable and searchable PDFs or TXT files. ・ Multiple - Print more than one page of a PDF on a single sheet of paper ![]() ・ Poster - Poster divides large PDF page(s) into multiple smaller Pages ・ Booklet - Booklet puts your pages side by side re-sorted for booklet printing, no matter what printer you have ・ Flatten - Flatten PDF to make the contents static ・ Background - Change the background (color or image) of the PDFs to comfort your eyes Add a unique prefix or suffix which can be a set number, case number, firm name or date ・ Bates number - Identify and retrieve information from your legal documents. ・ Header & Footer - Label each page of your PDF document with fully customized page numbers ・ Watermark - Add watermarks to keep your files safe and professional ・ Compare PDFs - Compare two versions of a PDF and catch every change ・ Rotate, delete, replace, and crop pages ・ Append - Insert another file into the existing file ・ Extract - Extract the desired pages to create a new PDF ・ Merge & Split - Split files into multiple files or combine multiple pages into a new single, searchable PDF Convert to PDF from images imported from Scanner and TXT files.Export from PDF to Word, PPT, Excel, RTF, Text, HTML, Image, CSV, and more.・Ensure document authenticity and integrity with digital signature. Work with static PDF forms created in Adobe Acrobat Create fillable PDF Forms from interactive field objects, such as buttons, check boxes and list boxes. ・Redact PDF - Black out sensitive information permanently ・Edit PDF text and change font size, style, color ・Table - Insert a table consisting of rows and columns of cells ・Link - Add and edit hyperlinks to redirect other destinations ・Stamps - Customize your PDF with custom, image and dynamic stamps ・Sign - Create multiple signatures for any situation with trackpad, keyboard or images ・Continuous Annotations - Add Comments Continuously ![]() ・Classic tools - Annotate PDF with highlight, underline, strikethrough, freehand, text box, anchored note, shape and etc ・ Bookmark specific pages or sections of PDFs ・ Create, Edit and Search outlines to easily navigate through the whole file ・ Presentation - Slideshow Mode to present your PDF as PPT ・ Reading modes - Multi-tab view, full-screen, page-fit, horizontal or vertical orientation, auto scroll, Night mode PDF Reader for Professional is your last PDF Viewer application you would ever need. Carry just your PDFs and make your presentations with them under the Presentation Mode, work becomes effortless and more productive with lighter PDFs! PDF Reader Pro offers even more - Edit text in PDFs, merge and combine multiple documents, split your PDF into several files, insert pages from another PDF, Convert PDF to Word and any other Microsoft Office® formats. Building on solid features such as Annotation, Edit, Form filling, OCR, Convert, Redact, Create, Sign, Bookmark and protect your PDF files, PDF Reader Pro allows you to maneuver through your PDF files. PDF Reader Pro is a PDF powerhouse that will fulfill all your document needs. Join the 90M users who are already working with PDF Reader Pro on their devices for Viewing, Editing, Commenting, Form Fill, Converting, Creating, OCR, and Signing PDFs You can copy and paste using the clipboard, or send it via the share sheet. You just copy a whole block of text - a name, address, phone number, etc. However, the very best thing about Cardhop, in my opinion, is how easy it makes adding new contacts. ![]() How to add a contact to Cardhop Add a new contact using the share sheet. That means you can use Cardhop as a lightweight customer-relations tool. For instance, the notes file is always available and has a button to add a text timestamp. The layout of this panel is almost exactly the same as in the stock Contacts app, only improved. The main panel shows your selected contact. You can map addresses, and easily edit contacts. You can paste in an unknown number, for example, along with a name, and add that number to the named contact. The “search” box, then, is really a command line for your contacts. You can type in something like call Bruce, and you’ll see the following: I actually have Bruce’s number blocked, but don’t tell him that. There’s a sidebar, which can be used to display a list of contacts, your favorites or one of several other views.Īt the top is a search box, but it does more than search. First is that it actually uses the iPad’s screen space. ![]() This is just like the way Fantastical, another great app from Cardhop developer Flexibits, integrates with your calendars.Ĭardhop offers a few standout features that become apparent the first time you open it. You can choose the kind of information which is shared using this card, along with aspects of its appearance.Cardhop might be the best contacts app on iOSĬardhop, which we showed you yesterday, uses your existing contacts database, so you don’t have to import anything or start from scratch. Finally, Cardhop allows users to configure a digital business card which can be easily shared using a QR code generated by the app. It’s also nice to see a dedicated Birthdays page, too, which should make it harder to forget the birthdays of your friends and family. First, there’s a Favorites page and a Recents page, both of which make it easier to find your most-used contacts. There are a few additional features in Cardhop which sweeten the deal. Cardhop then remembers your choice for the next time you send a message. ![]() When you first message a contact from inside Cardhop, the app also asks for the contact’s preferred messaging platform. Perhaps one of Cardhop’s best uses, though, is that the app lets iPhone and iPad owners store a wider range of contact information, and unifies all of the most popular chat apps (including WhatsApp and Facebook Messenger). You can configure exactly what appears in Cardhop’s search results. While the expected text-based commands are available (such as “Call Michael” or “FaceTime John”), Cardhop also lets users update contacts, get directions, or send messages using third-party apps like Facebook Messenger and Telegram simply by typing. When you launch the app, a text field encourages users to type commands into Cardhop and these provide a smart and speedy means of interacting with them. That shouldn’t sound so revolutionary – after all, it’s what contacts are designed for – but the feel of Cardhop is quite different. It’s called Cardhop – let’s take a closer look.Ĭardhop is based around the central idea of interacting with contacts. Fortunately, the App Store is here to help: a new offering from the folks behind the excellent Fantastical could offer the perfect Contacts app replacement. ![]() It does everything you need it to without being particularly special. Some of Apple’s built-in apps aren’t quite so impressive, and one of them is undoubtedly the Contacts app. Its smart functionality, elegant design, and hidden features make Cardhop a superb replacement for the Contacts app Overall I really enjoyed this anime, people should give it a try (unexpectedly, it even became one of my favourites). Even if you are more into romance, comedy, action or any genre that is not related to Shinsekai Yori, this anime is definitely worth watching and will probably open the doors to other anime series you never bothered to watch. The first two or three episodes really butters you up, but once you hit the fourth or fifth episode, I promise you, you will be hooked and you will just watch one episode after another. In terms of the enjoyment, this is not an anime that starts off on a high note and continues as such from there. The quality of art really makes you focus on the message the anime is trying to radiate to the viewer more than focusing of the wow factor on how amazing the art is. The characters and the environment in each of the scenes are drawn to a level of detail, not too simple, yet not to far in detail as well, just in the middle. The quality of the art and the animation is what you would expect of any anime standards that are out there today: clear, crisp and pleasing to the eye. Just youtube the battle theme, even if you have not watched the anime yet, it will entice your interests in this anime. Not to mention soundtrack produced in this amine, which is amazing. Every sound that you would not even care for is implemented in every episode and added in the appropriate places, at the appropriate times the echoing of the voices in a dim room, the rippling of water flowing from a stream. The sound is one of the areas this anime excels in. You will not see one character behaving as such and then the next episode they are being the polar opposite, everything is explained and shown very well. However, Shinsekai Yori pulls this off very smoothly, which is evidently seen with Saki and Satoru, which even applies to the supporting characters as well. With an anime that has twenty-five episodes, you would think it would not be enough time for proper character development from children to adults. There are a couple of anime who have attempted this children to adulthood metamorphosis motif within one season but they do not pull it off as well as Shinsekai Yori. The main characters start off as children and by the end of the anime they are adults, with proper illustration of character development. ![]() ![]() The characters in this anime are just something else, with Saki as it’s shining star. The plot of the show flows very nicely from episode to episode and just as we approach the climax, there’s a plot twist and the storyline from that point just flips upside down in a way you would never expect it to. From the beginning we follow a group of five children as they grow up in the anime and see how they develop within a community bounded by strict rules, and deal with the decisions they make that alter the course of their lives and the entire society they live in. ![]() Japan a thousand years from the present in a utopia where a portion of the population retain a special power called psychokinesis. However, I did give it a shot and after finishing the anime I can promise that it is truly a spectacle, a diamond in the ruff. ![]() During midst of 2013 I looked at Shinsekai Yori, the promotional picture did not catch my eye and the premises did not spark my interests. But I can promise that the majority of you, as did I, most likely did not have Shinsekai Yori as a pick. Rewind back to the dawn of fall 2012, you are looking at the fall 2012 anime chart, and you pick probably 5-7 anime you are going to watch. Everything starts off all nice and normal as you take a relaxing trip through pens belonging to many herbivore dinos. I never really got the obsession with Jurassic Park until I rode this water ride. Jurassic Park – Universal Studios: Hollywood Highlights of the actions include the pumping techno soundtrack and the vertical loops that wraps around the launch lift. I’m not sure why so many attractions are trying to gain revenge on their riders (Montezuma’s Revenge also comes to mind), but this stand-up coaster is a wonderful salute to the Batman franchise and the insanity of Edward Nigma. Spider-Man rules, so this attraction gets bonus points on that fact alone. You speed, web sling, and plunge through the streets of New York, watching Spidey battle the Sinister Syndicate. This is one of those classic 3-D movie attractions, but with the twist that you move from scene-to-scene in your ride vehicle. The Amazing Adventures of Spider-Man – Universal Studios: Islands of Adventure Sip and I are continually surprised the ride hasn’t been picked up by any of the other Disney parks. What starts out as a normal coaster turns (literally) into a very memorable one, when your vehicle begins spinning with the gravity and speed created by the ride track, at one point going into a dark room that gives space mountain a run for its money. ![]() When you combine a kid’s movie with a turbulent rollercoaster, you satisfy all of my needs! This attraction takes guests through the East Australian Current, riding on Crush the surfing turtle’s shell. So, let’s secure our personal belongings in the seat front pouch and hold on for dear life! Today’s subject may be a bit of a stretch, but given the word “loop” and “splash” are there, I wanted to discuss my favourite amusement park rides from around the world. I usually try to theme each day’s post in relation to the featured drink. ![]() Special thanks to /u/TheKookieMonster for letting me pester him to death.The battle continues as Sword Master defends the world from an all new, more dangerous army of invading Titans. It also shows the next few most efficient artifacts in a lighter shades.Īny errors/suggestions/formula help please message me! The most efficient artifact will be Bold and be the darkest shaded cell. There is a row for each damage type depending on what you want, for instance if you pet damage you should only look at the pet column, this already factors in tap damage conversion etc. ![]() For this sheet you need to enter your artifact values and on the right side you need to choose your build's gold type and your Hero damage type. Simple Artifact Optimizer - This is very similar to the SP Bonus Optimizer. It also shows the next few most efficient skills in a lighter shades. The most efficient skill will be Bold and be the darkest shaded cell. This will tell the optimizer which skills to ignore for you etc. On the right you need to choose if there are any active skills that you absolutely must use to reach your MS. It shows you the bonus per SP for the next level of all the skills and it is divided into damage type categories so look at the column that fits your build (so you can choose which skill gives you the best boost next). Sp Bonus Optimizer - This page has all the skills listed with your chosen levels from the interactive skill tree. It now interacts and shows SP required to unlock (although it still allows you to choose ranks regardless for SP optimizer). Interactive Trees - You can now rank up skills in each individual sheet and can see a cumulative SP spent in the top left. The only cells that you need to interact with on the sheets will be in Neon Green color! New User? - If you are unfamiliar with tools like this, Simply open the link, go to file and copy it for personal use. I took each simple tree out and made it into a combined sheet (scroll down), to help clear up some sheet clutter Added console to track Skill Points spent across pages! (just like in game).Ability to Allocate and Un-Allocate points across all skills.Skill tree already reflects the changes being made in the future 2.1.1 update(unless additional changes), most notably the Deadly Strike changes. Added offline/online user choice for T3 Rogue skills.Fixed T3 Rogue formula/Spoils of War formula.Added interactive console to track SP spent just like in game!.Added ignore column for SP! Simply switch to ignore for that skill to not be counted!. ![]() /r/BattleBouncers - Game Hive's brick breaking RPGĪlternating colored rows! Now highlights rows based on rank!./r/TapTycoon - For Game Hive's other incremental game./r/TapTitans - All about the original battle against the Titans./r/incremental_games - For more games where the numbers and progress just keep on going.The Titans are back, so pick up your sword and begin a new journey! Collect brand new equipment and customize your hero's looks and strengths to suit your playstyle. Form a clan and join forces with other players to defeat the almighty Titan Lords. ![]() Compete with other players around the world in global tournaments to show off your strength and earn amazing prizes. Unlock powerful skills, collect legendary artifacts, raise loyal pets to fight by your side, and hire a new band of devoted Heroes. Power up Sword Master in new ways to overcome the Titan's ever-increasing strength. The battle continues as Sword Master defends the world from an all new, more dangerous army of invading Titans. It is also close to the time zone used in the Middle East, which is the Arabia Standard Time ( AST). However, the time zone is close to the time zones used in other parts of Europe, such as Western European Time ( WET) and Central European Time ( CET). The time zones are not strict: they follow the boundaries of countries, because it would be inconvenient otherways. A term time zone describes an area where uniform standard time isused for the legal, social or economical purpose. Central European Time (CET) is used as standard time, while Central European Summer Time (CEST) is observed when Daylight Saving Time (DST) is in force. Why time zones were introduced Time zones are crucial for standartizing time across countries and regions. During the summer EEST - Eastern European Summer Time (UTC+3) is in use. How Many Time Zones Are There in Italy Italy has only one time zone. Paris +1h versus New York -5h, there is a difference of 6 hours, so Paris is always 6 hours ahead of New York in standard time. ahead of UTC (Coordinated Universal Time).The time offset from UTC can be written as +02:00. You can quickly check the current time difference between Europe and the US by viewing the current time zone at the top right of both countries. There are no other countries that use Eastern European Time. EET (Eastern European Time) is one of the well-known names of UTC+2 time zone which is 2h. Time zones: defined by their offset from Coordinated Universal Time (UTC) Photo. ![]() These countries are known for their rich cultural heritage, diverse landscapes, and vibrant cities. ![]() Full size map Printable time zone map Free printable time zone map for North. This means that during DST, Eastern European Time becomes UTC+03:00.Įastern European Time is used by the countries of Bulgaria, Cyprus, Estonia, Finland, Greece, Latvia, Lithuania, Moldova, Romania, and Ukraine, which are located in eastern Europe. Central European Time (CET) is used as standard time, while Central European. EET is two hours ahead of Coordinated Universal Time (UTC) and is abbreviated as UTC+02:00.ĭuring Daylight Saving Time ( DST), the clock is turned ahead by one hour in the spring and turned back by one hour in the fall. ![]() It will become active again after the next clock change as Daylight Saving Time begins or ends. Eastern European Time (EET) is a time zone used in eastern Europe, including Bulgaria, Cyprus, Estonia, Finland, Greece, Latvia, Lithuania, Moldova, Romania, and Ukraine. The above time zone is used during other parts of the year. ![]() Simeon also hosts open “office hours” every Monday and Tuesday for anyone interested in signing up to receive 1:1 guidance on Firefox for Android extension development. Here are recorded webinars from October (an introduction to mobile extension migration) and November (setup, testing, debugging). Senior Developer Relations Engineer Simeon Vincent recently hosted two webinars to help developers work through common migration hurdles. There’s still time to make your desktop extension compatible with Firefox for Android if you want to be part of the December 14 launch. Try a few out! Get your Firefox desktop extension ready for Android You can find them listed beneath the Recommended Extensions collection on that AMO Android page. And just for fun and to offer a taste of what’s to come, we also released a couple dozen new open extensions for Android. In anticipation of the launch of open extensions on Android, we just added a link to “ Explore all Android extensions” on AMO’s Android page to make it easy to discover new content. We couldn’t be more thankful to our developer community for embracing this exciting moment.” “Just a few weeks ago it looked like we might have a couple hundred Android extensions for launch, but now we can safely say AMO will have 400+ new Firefox for Android extensions available on December 14. “We’ve been so impressed with developer enthusiasm and preparation,” said Giorgio Natili, Firefox Director of Engineering. Starting December 14, 2023, extensions marked as Android compatible on (AMO) will be openly available to Firefox for Android users. Open extensions on Firefox for Android debut December 14 (but you can get a sneak peek today) Have you found any Firefox for Android bugs? Do tell! If you’ve already embarked on the mobile extension journey and have questions/insights/feedback to offer as we continue to optimize the mobile development experience, we invite you to join the discussion about top APIs missing on Firefox for Android. Let’s see where this goes.Īre you a developer who hasn’t migrated your desktop extension to Firefox for Android yet? Here’s a good starting point for developing extensions for Firefox for Android. It’s a strong start to an exciting new frontier of mobile browser customization. More than 450 Firefox for Android extensions are now discoverable on the (AMO) Android homepage. Woo-hoo you did it! Hundreds of add-on developers heeded the call to make their desktop extensions compatible for today’s debut of a new open ecosystem of Firefox for Android extensions. ![]() ![]() Thus, hydroxocobalamin acts as a nitric oxide scavenger to limit the significant dysregulated release of nitric oxide seen in severe sepsis. In a significant vasodilatory state such as sepsis, inducible nitric oxide synthase (iNOS) expression, the precursor catalyst of nitric oxide, is increased up to one-thousand fold 8. In addition, the nitrosylcobalamin metabolite itself has anti-inflammatory properties including inhibition of NF-κB and hydrogen sulfide 8. Interestingly, nitrosylcobalamin holds tightly onto nitric oxide, inhibiting nitric oxide’s vasodilatory effects and increasing systemic blood pressure 7. It turns out that this same hydroxyl group can also be displaced by nitric oxide (NO-) in the blood stream to yield nitrosylcobalamin. In treating cyanide poisoning, this hydroxyl group is easily displaced by toxic cyanide (CN-) yielding cyanocobalamin, a benign compound that is renally excreted 7. The prefix ‘hydroxo’ in hydroxocobalamin refers to a hydroxyl group (-OH) that is bounded to a central cobalt. With some understanding of the chemical structure of hydroxocobalamin, the mechanism of hypertension is well understood. In its original approval, the side effect profile included hypertension. The drug was originally marketed with an FDA approval for cyanide toxicity 6. High-dose hydroxocobalamin (vitamin B12) is gaining traction as a potential new approach to reduce the need for conventional vasopressors including catecholamines, vasopressin, and angiotensin II. Vitamin B12, hydroxocobalamin, may be the next in line for evaluation, scrutiny, and debate. With this result, the community has explored alternative therapies to manage septic shock. Most recently, a large trial showed that patients in intensive care who received vitamin C therapy had a higher risk of death or persistent organ dysfunction 5. This fascinating result led to several prospective trials and meta-analyses 3, 4. A controversial retrospective analysis to evaluate the efficacy of vitamin C demonstrated a major reduction in mortality, AKI, and vasopressor duration 2. Vitamin C is thought to have antioxidant effects that attenuate tissue injury mediated by inflammation 1. All rights reserved.In recent years, the critical care community has debated the benefits of vitamin C in septic shock. Hydroxocobalamin/administration & dosage methylene blue/adverse effects methylene blue/therapeutic use postoperative complications/drug therapy vasoplegia/drug therapy.Ĭopyright © 2021 Elsevier Inc. In adult patients undergoing cardiothoracic surgery using CPB with VS, the ability to reduce vasopressor use was similar with hydroxocobalamin compared with methylene blue. There were no significant between-group differences in percentage change in norepinephrine equivalents or vasoactive inotropic score at each timepoint. Baseline demographics, surgical characteristics, and vasoactive medications were similar between groups. After matching, 66 patients in the methylene blue group were included in the analysis. Of the 142 included patients, 120 received methylene blue and 22 received hydroxocobalamin. Patients were included who received either hydroxocobalamin (5,000 mg) or methylene blue (median 1.2 mg/kg) for VS in the operating room during the index surgery or in the intensive care unit up to 24 hours after CPB separation. Eligible patients who received methylene blue were matched 3:1 with patients who received hydroxocobalamin based on sequential organ failure assessment score, preoperative mechanical circulatory support, CPB duration, and use of pre-CPB vasopressors, angiotensin-converting enzyme inhibitors, or beta-blockers.Ī quaternary care academic medical center.Īdult patients who underwent cardiac surgery with CPB from July 2013 to June 2019. The primary endpoints were the percentage change in vasopressor use at 30, 60, and 120 minutes, characterized as both norepinephrine equivalents and vasoactive inotropic score. To compare hydroxocobalamin and methylene blue for the treatment of vasopressor-refractory vasoplegic syndrome (VS) after adult cardiac surgery with cardiopulmonary bypass (CPB).Ī retrospective, propensity-matched, cohort study was performed. ![]() ![]() If you are wondering how can i improve video quality, then worry not. Part 3: How to Improve A Video Quality with HitPaw Video Enhancer: Step-by-Step With these robust tools and easy batch processing, HitPaw Video Enhancer makes it simple to breathe new life into your video library. Enhances anime and animated videos for flawless quality at higher resolutions.Ensures faces remain clearly defined when enlarging video.Adds realistic, vibrant color to black-and-white videos.Removes background noise and graininess while retaining critical detail.Enlarges video resolution up to 8K without losing sharpness or introducing distortion.Fixes issues like glitches, noise, and blur to restore video quality.The ai improve video quality and video repair are the famous features of HitPaw Video Enhancer: As the best video quality improver, HitPaw Video Enhancer can easily reduce noise from your videos. HitPaw Video Enhancer stands out from other editors thanks to its specialized, tailored AI models that allow both automatic and extensively customized video enhancements. With just a few easy clicks, it leverages cutting-edge, revolutionary deep learning technology to seamlessly repair issues and substantially upgrade video resolution without compromising pristine quality. HitPaw Video Enhancer is an ingenious, AI-powered video editing software that can dramatically and automatically enhance lackluster video quality through intelligent upscaling, noise reduction, colorization, and more. Part 2: The Most Amazing Software to Improving A Video Seamlessly ![]()
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